Cardiology
As the world’s leading cause of death, cardiovascular disease places an enormous burden on patients, families and healthcare systems.1 We’re developing radiodiagnostics that aim to detect disease earlier, guide more confident decisions and have the potential to improve outcomes.
A need for what’s next in
cardiovascular care
Despite progress in prevention, clinicians face critical gaps in diagnosing and managing cardiovascular disease (CVD). Symptoms vary widely, and traditional imaging often relies on structural changes that appear late in disease progression. Molecular imaging with radiodiagnostics can highlight details inside the heart that may prove challenging for conventional methods.
global cause of disease burden is CVD1
~1 in 3 of all annual global deaths are attributed to CVD1
Cardiology focus areas
Our work in cardiovascular disease is concentrated on two high-need areas where molecular imaging may support diagnosis and guide care.
Cardiac amyloidosis
Cardiac amyloidosis is a rare, life-threatening, progressive condition often underdiagnosed as a cause of heart failure.2 Unstable proteins misfold and aggregate into amyloid fibrils that deposit in the heart, stiffening ventricles and driving symptoms.3 By visualizing deposition at the molecular level, we aim to help clinicians detect disease earlier and monitor progression over time.
Thrombus imaging
A thrombus is a blood clot formed inside a vein, artery or the heart via platelet activation and fibrin formation.4 These clots can migrate, causing high-risk events like deep vein thrombosis or pulmonary embolism.5 Our research focuses on imaging active clot formation, targeting biological signals with the goal of providing actionable insights for informed treatment and monitoring.
Putting patients at the heart of our work
We ground ourselves in our purpose to Find, Fight and Follow® disease to deliver better patient outcomes. In cardiology, that means developing innovative radiodiagnostics in areas of high unmet need with the aim to deliver earlier answers and support informed decisions throughout the patient journey.
REFERENCES
1. Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023. JACC. Published December 2, 2025. Accessed February 5, 2026. https://doi.org/10.1016/j.jacc.2025.08.015 2. Cardiac Amyloidosis as a Rare Cause of Heart Failure: A Case Report. National Library of Medicine. Published April 2019. Accessed January 26, 2026. https://pubmed.ncbi.nlm.nih.gov/30946343/ 3. Cardiac Amyloidosis. National Library of Medicine. Published May 3, 2025. Accessed January 26, 2026. https://www.ncbi.nlm.nih.gov/books/NBK580521/ 4. Thrombosis. National Library of Medicine. Published February 12, 2024. Accessed January 26, 2026. https://www.ncbi.nlm.nih.gov/books/NBK538430/ 5. Thromboembolic Event. National Library of Medicine. Published May 22, 2023. Accessed January 26, 2026. https://www.ncbi.nlm.nih.gov/books/NBK549877/
